Senate committee approves classifying xylazine as controlled substance Apr 3, 2025 | Opioids, Top Stories A Senate committee approved a plan Wednesday that would relabel xylazine, a tranquilizer often mixed with fentanyl, as a controlled substance.To access this content, you must purchase 1 Year Health News Illinois Subscription or 1 Year Group Subscription - Up to 5 Users, or log in if you are a member.